America's North Shore Journal

Supporting the Ninth Amendment

Category: Military

Shark Antibodies Make a Splash

Ribbon structure of a shark-derived single-domain antibody

As a cost-effective alternative to both conventional and camelid single-domain antibodies for therapeutic, detection and biotechnology applications, recombinant production enables a more uniform and consistent product. Stabilizing high melting temperatures can greatly reduce the logistical cost of shipping and storing for detection, diagnostics and therapeutic reagents as they would no longer need to be maintained at refrigerated temperatures. This would lower development costs for new technologies focused on protecting the warfighter and civilian populations.

Turnkey Detection: Rapid Diagnostics in the Field

schematic showing the fluorescent signal obtained from the RNA of the MERS coronavirus

This new diagnostic device will allow quicker point-of-care testing of infected warfighters allowing for more rapid treatment and troop safety. After analytical comparisons with current CDC kits, the next step will be to gain ‘Emergency Use Authorization.’ This will accelerate the FDA development process, allowing the diagnostic tool to reach the warfighter sooner.

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